Xtend-Life Ingredient 3,3′-diindolylmethane (DIM)

DIM Background and Benefits

DIM is an abbreviation for 3,3′-diindolylmethane, which is composed of a methane group with two indole groups attached to it. The primary natural source of DIM is the digestion of cruciferous vegetables. These vegetables are members of the cabbage family, which also include broccoli, Brussels sprouts, cauliflower and kale. The health benefits of cruciferous vegetables are partially due to the effects of DIM.

Cruciferous vegetables contain glucobrassicin, which is a type of glucosinolate. The digestion of glucobrassicin breaks down into indole-3-carbinol and thiocyanate when catalyzed by the enzyme myrosinase, which is also present in cruciferous vegetables. Indole-3-carbinol quickly breaks down into DIM and other metabolites during the acid-mediated process of digestion.

Heat breaks down myrosinase, so cooking vegetables reduces the bioavailability of DIM. However, some of its bioavailability is still retained since human intestines also contain some myronsinase. Water also reduces the availability of DIM since glucobrassicin is water soluble. Low-temperature steaming is therefore the best method of cooking vegetables while preserving the bioavailability of glucobrassicin.

The primary biochemical role of DIM is to modify the metabolism of estrogen so that it produces more 2-hydroxy estrogen metabolites. The most significant result of this change is a decrease in 16-hydroxyestrone production and an increase in 2-hydroxyestrone production.

Uses of DIM

The uses of DIM generally result from its ability to manage hormone levels, especially testosterone and estrogen. These uses include prostate health support, antioxidant support, weight management and the management of menstrual symptoms.

Signs You May Need DIM

The signs that you may need DIM supplements are generally caused by unhealthy levels of testosterone and estrogen. The symptoms of premenstrual syndrome (PMS) are some of the most common indications that women may need DIM.

Men may benefit from DIM if they have an unhealthy testosterone level, which can cause low moods and a poor libido. Men who wish to increase muscle mass with exercise may also want to take DIM.

Other Ingredients That May Be Of Interest

Chrysin - Chrysin is a flavone found in several plants, especially passion flowers such as Passiflora incarnata and Passiflora caerulea. Oroxylum indicum, commonly known as the Indian trumpet flower, is also a significant source of chrysin. The most common use of chrysin as a health supplement is in bodybuilding, primarily for the purpose of supporting testosterone production. It is also used to manage feelings of anxiety.

Synonyms and Similar Forms of DIM

3,3′-diindolylmethane, DIM 3'3

Products containing DIM

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